Lab in late 2019
Lab in mid 2020
Rachel Perry, Ph.D. (PI)
Rachel earned her Ph.D. and completed her postdoctoral training at Yale in the lab of Dr. Gerald Shulman, where she focused on the development and application of novel stable isotope tracer methods to model hepatic metabolism under physiological and pathophysiological conditions. In her own lab at Yale, Rachel studies how metabolism intersects with various physiological and pathophysiological states, including cancer and inflammation. This is, quite sincerely, her dream job.
Ngozi Akingbesote (PhD student)
Ngozi is a first year graduate student in the Perry lab. She is expertly juggling multiple projects related to metabolic scaling, exercise and lung cancer, and the metabolic drivers of hepatocellular carcinoma.
Aray Beisenbayeva (remote high school student)
Aray is a high school student in Kazakhstan. She works with Shyryn Ospanova to perform a data analysis project to better understand the social and biochemical determinants of prognosis in lung cancer.
Hailey Edelman (undergraduate student)
Hailey is a first-year undergraduate student at Yale. Her project in the Perry lab, in part working with Brooks Leitner, involves exploring the mechanisms that modulate exercise performance and recovery in rodents, and exploring potential therapies to enhance these processes.
Alex is an undergraduate student who has joined the Perry lab with goals of better defining how in vitro and in vivo tumor cell metabolism can be modulated to improve outcomes in cancer.
Alex Halberstam (undergraduate student)
Brooks Leitner (MSTP student)
Brooks is a third-year MD/PhD student whose credentials include serving as a personal trainer to humans and – in the lab – to mice. His project focuses on understanding the mechanism of how recovery from exercise is orchestrated by immunometabolic communication between organs. His first first-author paper in the lab is based on work done during his five-week rotation (!), and it will not be his last.
Chigoziri Konkwo (MD student)
Chigoziri is a second year MD student at Yale who joined our lab virtually during the pandemic, during which he did considerable genomics data analysis and wrote a review, and is continuing with an in person project aiming to understand why, seemingly paradoxically, obesity is protective against lung cancer and improves the response of this disease to immunotherapy, in contrast to numerous other tumor types, in which obesity increases incidence and worsens prognosis.
Zongyu Li (PhD student)
Zongyu is a third-year Ph.D. student in Cellular & Molecular Physiology. Before the end of his research rotation, he was already producing publishable-quality FACS data (!), and has not slowed down from there. Zongyu’s two projects include delving into how a novel inflammatory mediator may improve hypoglycemia counterregulation, and characterizing immunometabolic crosstalk in cancer.
Shyryn Ospanova (remote high school student)
Shyryn is a high school student in Kazakhstan. She works with Aray Beisbenbayeva on a data analysis project to better understand the social and biochemical determinants of prognosis in lung cancer.
Stephan Siebel MD, PhD (Associate Research Scientist)
Dr. Siebel has considerable experience (and doctorates) in flux methodology and genetics. In the Perry lab, he works to understand how alterations in various metabolic pathways promote hepatocellular carcinoma pathogenesis. In addition, he is our local mass spec expert – a skill which cannot be undervalued!
Xinyi Zhang (PhD student)
Xinyi is a second-year Ph.D. student in Cellular & Molecular Physiology. She rotated in the lab during the COVID-19 pandemic, and we are delighted that she has decided to stay! Her project will focus on the use of metabolic therapy in melanoma, a tumor type that has traditional not been associated with metabolic changes but has given us some interesting hints of metabolic vulnerabilities that may be exploitable.
Wanling Zhu (research technician)
Wanling is a research technician who works 20% of the time in the Perry lab. She has been a crucial participant in hundreds of our in vivo mouse studies and is a skilled surgeon: few people we know can place a catheter in a vein that’s just 0.2 mm wide with almost 100% survival rate, but Wanling can!
We are hiring!
While we do not currently have open positions posted, we are open to welcoming candidates whose interests line up with the priorities of the lab. If you are interested, please contact Rachel.
Alex Halberstam (undergraduate student)
Alex is an undergraduate student who has joined the Perry lab with goals of better defining how in vitro and in vivo tumor cell metabolism can be modulated in